CAPTOPRIL; HYDROCHLOROTHIAZIDE (KAP toe pril; hye droe klor oh THYE a zide) is a combination of a diuretic and an ACE inhibitor. It is used to treat high blood pressure.
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take this medicine on an empty stomach, at least 1 hour before meals. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking this medicine except on the advice of your doctor or health care professional.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
changes in vision
decreased amount of urine passed
fast or irregular heart beat
feeling faint or lightheaded, falls
persistent dry cough
redness, blistering, peeling or loosening of the skin, including inside the mouth
signs and symptoms of high blood sugar such as being more thirsty or hungry or having to urinate more than normal. You may also feel very tired or have blurry vision.
swelling of your hands or feet
unusual bleeding or bruising
worsened gout pain
yellowing of the eyes or skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
change in sex drive or performance
Do not take this medication with any of the following medications:
This medicine may also interact with the following:
barbiturates like phenobarbital
blood pressure medicines
corticosteroids like prednisone
diuretics, especially potassium-sparing diuretics like triamterene, spironolactone or amiloride
MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
medicines for angina like nitroglycerin
medicines that treat or prevent blood clots like warfarin
medicines used to treat gout
NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
potassium salts or potassium supplements
prescription pain medicines
skeletal muscle relaxants like tubocurarine
some cholesterol-lowering medications like cholestyramine or colestipol
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Keep out of the reach of children.
Store at room temperature below 30 degrees C (86 degrees F). Protect from moisture and light. Keep container tightly closed. Throw away any unused medicine after the expiration date.
They need to know if you have any of these conditions:
bone marrow disease
heart or blood vessel disease
if you are on a special diet like a low salt diet
immune system problems, like lupus
previous swelling of the tongue, face, or lips with difficulty breathing, difficulty swallowing, hoarseness, or tightening of the throat
recent heart attack or stroke
an unusual or allergic reaction to captopril, hydrochlorothiazide, sulfa drugs, other medicines, insect venom, foods, dyes, or preservatives
pregnant or trying to get pregnant
Visit your doctor or health care provider for regular checks on your progress. Check your blood pressure as directed. Ask your doctor or health care provider what your blood pressure should be and when you should contact him or her. Call your doctor or health care provider if you notice an irregular or fast heart beat.
You must not get dehydrated. Ask your doctor or health care provider how much fluid you need to drink a day. Check with him or her if you get an attack of severe diarrhea, nausea and vomiting, or if you sweat a lot. The loss of too much body fluid can make it dangerous for you to take this medicine.
Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care provider or pharmacist for more information.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this drug affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol can make you more drowsy and dizzy. Avoid alcoholic drinks.
This medicine may increase blood sugar. Ask your healthcare provider if changes in diet or medicines are needed if you have diabetes.
Avoid salt substitutes unless you are told otherwise by your doctor or health care provider.
This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.
Do not treat yourself for coughs, colds, or pain while you are taking this medicine without asking your doctor or health care provider for advice. Some ingredients may increase your blood pressure.