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AMIODARONE (a MEE oh da rone) is an antiarrhythmic drug. It helps make your heart beat regularly. Because of the side effects caused by this medicine, it is only used when other medicines have not worked.
This medicine is for infusion into a vein. It is given by a health care professional in a hospital or clinic setting.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
cough with or without blood
fast, irregular heartbeat
feeling faint or light-headed
intolerance to heat or cold
pain and swelling of the scrotum
pain, tingling, numbness in feet, hands
problems with balance, talking, walking
redness, blistering, peeling or loosening of the skin, including inside the mouth
spitting up blood
unusual or uncontrolled movements of body
unusually weak or tired
weight gain or loss
yellowing of eyes, skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
change in sex drive or performance
loss of appetite
Do not take this medicine with any of the following medications:
certain antibiotics like erythromycin, gemifloxacin, levofloxacin, pentamidine
certain medicines for depression like amoxapine, tricyclic antidepressants
certain medicines for fungal infections like fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole
certain medicines for irregular heart beat like disopyramide, dofetilide, dronedarone, ibutilide, propafenone, sotalol
certain medicines for malaria like chloroquine, halofantrine
phenothiazines like chlorpromazine, mesoridazine, thioridazine
red yeast rice
This medicine may also interact with the following medications:
antiviral medicines for HIV or AIDS
certain medicines for blood pressure, heart disease, irregular heart beat
certain medicines for cholesterol like atorvastatin, cerivastatin, lovastatin, simvastatin
certain medicines for hepatitis C like sofosbuvir and ledipasvir; sofosbuvir
certain medicines for seizures like phenytoin
certain medicines for thyroid problems
certain medicines that treat or prevent blood clots like warfarin
other medicines that prolong the QT interval (cause an abnormal heart rhythm)
rifabutin, rifampin, rifapentine
St. John's Wort
This does not apply.
This drug is given in a hospital or clinic and will not be stored at home.
They need to know if you have any of these conditions:
other heart problems
an unusual or allergic reaction to amiodarone, iodine, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
Your condition will be monitored closely when you first begin therapy. This drug is first started in a hospital or other monitored health care setting. Once you are on maintenance therapy, visit your doctor or health care professional for regular checks on your progress. Because your condition and use of this medicine carry some risk, it is a good idea to carry an identification card, necklace or bracelet with details of your condition, medications, and doctor or health care professional.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.
This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.
Your eyes may get dry while you are using this medicine. It may be helpful to use a lubricating eye solution or artificial tears solution. Check with your doctor or health care professional for regular eye examinations.
If you are going to have surgery or a procedure that requires contrast dyes, tell your doctor or health care professional that you are taking this medicine.