TOLVAPTAN (tol VAP tan) is used to treat low levels of sodium in the blood.
Take this medicine by mouth with a glass of water. This medicine will be started in a hospital. You may need to continue this medicine at home. Follow the directions on the prescription label. Do not stop and re-start this medicine on your own. You may need to go back to a hospital to re-start this medicine. You can take it with or without food. If it upsets your stomach, take it with food. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor's advice.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
black or tarry stools
fast, irregular heartbeat
uncontrollable body movements
unusually weak or tired
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
increased hunger or thirst
Do not take this medicine with any of the following medications:
certain antibiotics like chloramphenicol, clarithromycin, dalfopristin; quinupristin, telithromycin
certain antiviral medicines for HIV or AIDS like atazanavir, cobicistat, darunavir, delavirdine, fosamprenavir, indinavir, nelfinavir, ritonavir, saquinavir, tipranavir
certain medicines for fungal infection like ketoconazole, itraconazole, posaconazole, voriconazole
This medicine may also interact with the following medications:
certain antibiotics like erythromycin, rifampin, rifabutin, and rifapentine
certain medicines for blood pressure, heart disease, irregular heart beat
certain medicines for seizures like carbamazepine, phenobarbital, phenytoin
St. John's Wort
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.
They need to know if you have any of these conditions:
cannot feel if you are thirsty
history of alcohol abuse problem
an unusual or allergic reaction to tolvaptan, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
Your condition will be monitored carefully while you are receiving this medicine.
Check with your doctor or health care professional if you get an attack of severe diarrhea, nausea and vomiting, or if you sweat a lot. The loss of too much body fluid can make it dangerous for you to take this medicine.
You may need blood work done while you are taking this medicine.