LEPIRUDIN is an anticoagulant. It is used in a hospital setting to help prevent blood clots.
This medicine is for injection or infusion into a vein. It is given by a health care professional in a hospital or clinic setting.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
feeling faint or lightheaded, falls
signs and symptoms of bleeding such as bloody or black, tarry stools; red or dark-brown urine; spitting up blood or brown material that looks like coffee grounds; red spots on the skin; unusual bruising or bleeding from the eye, gums, or nose
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
pain, redness, or irritation at site where injected
Do not take this medicine with any of the following medications:
aspirin and aspirin-like medicines
medicines that treat or prevent blood clots like warfarin or heparin
This medicine may also interact with the following medications:
NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
This does not apply.
This drug is given in a hospital or clinic and will not be stored at home.
They need to know if you have any of these conditions:
bleeding disorders or hemophilia
high blood pressure
infection of the heart valves
lumbar puncture or spinal anesthesia
recent surgery or trauma
stomach or intestinal ulcers
weak or unstable blood vessels
an unusual or allergic reaction to lepirudin, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
Visit your doctor or health care professional for regular check ups. Your condition will be monitored carefully while you are receiving this medicine.
Notify your doctor or health care professional and seek emergency treatment if you develop breathing problems; changes in vision; chest pain; severe, sudden headache; pain, swelling, warmth in the leg; trouble speaking; sudden numbness or weakness of the face, arm, or leg. These can be signs that your condition has gotten worse.
Avoid sports and activities that might cause injury while you are using this medicine. Severe falls or injuries can cause unseen bleeding. Be careful when using sharp tools or knives. Consider using an electric razor. Take special care brushing or flossing your teeth. Report any injuries, bruising, or red spots on the skin to your doctor or health care professional.
If you are going to have surgery, tell your doctor or health care professional that you have received this medicine.