Text SUPPORT1 to 21825 to learn if you may be eligible for financial support with your medication(s).Msg&DataRatesMayApply. Msg freq varies. Terms apply. Text HELP for help. Text STOP to end.
DARUNAVIR (da ROON a veer) is an antiretroviral medicine. It is used with other medicines to treat HIV. This medicine is not a cure for HIV. This medicine can lower, but not fully prevent, the risk of spreading HIV to others.
Take this medicine by mouth. Follow the directions on the prescription label. Shake well before using. Take this medicine with food. Use a specially marked spoon or dropper to measure each dose. Ask your pharmacist if you do not have one. Household spoons are not accurate. Take your medicine at regular intervals. Do not take your medicine more often than directed. For your anti-HIV therapy to work as well as possible, take each dose exactly as prescribed. Do not skip doses or stop your medicine even if you feel better. Skipping doses may make the HIV virus resistant to this medicine and other medicines. Do not stop taking except on your doctor's advice.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 3 years for selected conditions, precautions do apply.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
increased hunger or thirst
muscle or joint pain
redness or swelling of the eyes
redness, blistering, peeling or loosening of the skin, including inside the mouth
signs of infection like fever or chills; cough; sore throat; pain or trouble passing urine
signs of liver injury like dark yellow or brown urine; generally ill feeling of flu-like symptoms; light-colored stools; loss of appetite; nausea or vomiting; right upper belly pain; unusually weak or tired; yellowing of the eyes or skin
signs and symptoms of high blood sugar such as being more thirsty or hungry or having to urinate more than normal. You may also feel very tired or have blurry vision.
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
weight gain around waist, back, or thinning of face, arms, legs
Do not take this medicine with any of the following medications:
certain medicines for blood pressure, heart disease, irregular heart beat like dronedarone, ivabradine, ranolazine
colchicine (if you have liver or kidney problems)
medicines for cholesterol like lomitapide, lovastatin, simvastatin
medicines for headaches like dihydroergotamine, ergonovine, ergotamine, methylergonovine
red yeast rice
sildenafil (for the treatment of pulmonary arterial hypertension)
St. John's Wort
This medicine may also interact with the following medications:
certain antibiotics like clarithromycin, rifabutin, rifapentine
certain other antiviral medicines for HIV like didanosine, indinavir, maraviroc, saquinavir, or lopinavir; ritonavir
certain medicines for anxiety or sleep like buspirone, diazepam, estazolam, zolpidem
certain medicines for blood pressure and heart disease like amlodipine, carvedilol, diltiazem, felodipine, metoprolol, nicardipine, nifedipine, timolol, verapamil
certain medicines for cancer like dasatinib, nilotinib, vinblastine, vincristine
certain medicines for depression like amitriptyline, desipramine, imipramine, nortriptyline, paroxetine, sertraline, and trazodone
certain medicines for erectile dysfunction like avanafil, sildenafil, tadalafil, vardenafil
certain medicines for fungal infection like itraconazole, ketoconazole, posaconazole, voriconazole
certain medicines for hepatitis infection like boceprevir, simeprevir
certain medicines for psychotic disturbances like quetiapine, risperidone, thioridazine
certain medicines for seizures like carbamazepine, phenobarbital, phenytoin
certain medicines that treat or prevent blood clots like apixaban, rivaroxaban, warfarin
female hormones, like estrogens and progestins and birth control pills
medicines for cholesterol like atorvastatin, pravastatin, rosuvastatin
medicines for irregular heart beat like amiodarone, bepridil, digoxin, disopyramide, flecainide, lidocaine, mexiletine, propafenone, quinidine
medicines that lower your chance of fighting infection like cyclosporine, everolimus, sirolimus, tacrolimus
narcotic medicines for pain such as buprenorphine, buprenorphine; naloxone, methadone
steroid medicines like betamethasone, budesonide, ciclesonide, dexamethasone, fluticasone, methylprednisolone, mometasone, prednisolone, triamcinolone
If you miss a dose, take it as soon as you can. If you usually take your medicine once a day and your next dose is to be taken in less than 12 hours, then do not take the missed dose. If you usually take your medicine twice a day and your next dose is to be taken in less than 6 hours, then do not take the missed dose. Take the next dose at your regular time. Do not take double or extra doses.
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.
They need to know if you have any of these conditions:
an unusual or allergic reaction to darunavir, sulfa medicines, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
Visit your doctor or health care provider for regular check ups. Discuss any new symptoms with your doctor. You will need to have important blood work done while on this medicine.
HIV is spread to others through sexual or blood contact. Talk to your doctor about how to stop the spread of HIV.
Birth control pills may not work properly while you are taking this medicine. Talk to your doctor about using an extra method of birth control. Women who can still have children must use a reliable form of barrier contraception, like a condom or diaphragm.
This medicine may increase blood sugar. Ask your healthcare provider if changes in diet or medicines are needed if you have diabetes.