CHLORPROMAZINE (klor PROE ma zeen) has many different uses. It is used to treat certain mental and behavioral disorders. It is also used to control nausea and vomiting, nervousness before surgery, and hiccups that will not go away. It is also used to treat episodes of porphyria and in combination with other medicines to treat tetanus.
The medicine is for injection into a muscle or infusion into a vein. It is given by a health care professional in a hospital or clinic setting.
Talk to your pediatrician regarding the use of this medicine in children. While this medicine may be prescribed for children as young as 6 months of age for selected conditions, precautions do apply.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
abnormal production of milk
breast enlargement in both males and females
changes in vision
fast, irregular heartbeat
fever, chills, sore throat
signs and symptoms of high blood sugar such as being more thirsty or hungry or having to urinate more than normal. You may also feel very tired or have blurry vision.
signs and symptoms of liver injury like dark yellow or brown urine; general ill feeling or flu-like symptoms; light-colored stools; loss of appetite; nausea; right upper belly pain; unusually weak or tired; yellowing of the eyes or skin
signs and symptoms of low blood pressure like dizziness; feeling faint or lightheaded, falls; unusually weak or tired
trouble passing urine or change in the amount of urine
uncontrollable movements of the arms, face, head, mouth, neck, or upper body
unusual bruising or bleeding
unusually weak or tired
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
pain, redness, or irritation at site where injected
Do not take this medicine with any of the following medications:
This medicine may also interact with the following medications:
antihistamines for allergy, cough, and cold
certain medicines for anxiety or sleep
certain medicines for bladder problems like oxybutynin, tolterodine
certain medicines for depression like amitriptyline, fluoxetine, sertraline
certain medicines for stomach problems like dicyclomine, hyoscyamine
certain medicines for travel sickness like scopolamine
general anesthetics like halothane, isoflurane, methoxyflurane, propofol
levodopa or other medicines for Parkinson's disease
medicines for high blood pressure
medicines for seizures like phenobarbital, primidone, phenytoin
medicines that relax muscles for surgery
narcotic medicines for pain
other medicines that prolong the QT interval (an abnormal heart rhythm)
This does not apply.
This drug is given in a hospital or clinic and will not be stored at home.
They need to know if you have any of these conditions:
blockage in your bowel
have trouble controlling your muscles
history of irregular heartbeat
if you often drink alcohol
low blood counts, like low white cell, platelet, or red cell counts
low blood pressure
lung or breathing disease, like asthma
trouble passing urine
an unusual or allergic reaction to chlorpromazine, sulfites, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
Your condition will be monitored carefully while you are receiving this medicine. Tell your health care professional if symptoms do not start to get better or if they get worse.
You may get drowsy, dizzy, or have blurred vision. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol can increase possible dizziness or drowsiness. Avoid alcoholic drinks.
This drug can cause problems with controlling your body temperature. It can lower the response of your body to cold temperatures. If possible, stay indoors during cold weather. If you must go outdoors, wear warm clothes. It can also lower the response of your body to heat. Do not overheat. Do not over-exercise. Stay out of the sun when possible. If you must be in the sun, wear cool clothing. Drink plenty of water. If you have trouble controlling your body temperature, call your health care provider right away.
This medicine may increase blood sugar. Ask your health care provider if changes in diet or medicines are needed if you have diabetes.
This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.
Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your doctor if the problem does not go away or is severe.
If you are going to have surgery, tell your doctor or health care professional that you are taking this medicine.