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CYCLOSPORINE (SYE kloe spor een) is used to decrease the immune system's response to a transplanted organ.
This medicine is for infusion into a vein. It is given by a health care professional in a hospital or clinic setting.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
changes in vision
high blood pressure
increased urge to urinate or frequent urination
numbness or tingling in the hands and feet
severe stomach pain
yellowing of the eyes or skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
bleeding or tender gums, overgrowth of gum tissue
excessive hair growth on the face or body
Do not take this medicine with any of the following medications:
red yeast rice, monascus purpureus
St. John's wort
This medicine may also interact with the following medications:
female hormones, including contraceptive or birth control pills
medicines for fungal infections like amphotericin B, fluconazole, itraconazole, terbinafine, and ketoconazole
medicines for blood pressure like diltiazem, nicardipine, verapamil, enalapril, ramipril, and losartan
medicines for cholesterol like lovastatin, simvastatin, atorvastatin, and fenofibrate
medicines for HIV infection like indinavir, nelfinavir, ritonavir, and saquinavir
medicines that suppress the immune system
NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
steroid medicines like prednisone or cortisone
This does not apply.
This drug is given in a hospital or clinic and will not be stored at home.
They need to know if you have any of these conditions:
an unusual or allergic reaction to cyclosporine, alcohol, castor oil, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
Your condition will be monitored carefully while you are receiving this medicine. You will need important blood work while you are taking this medicine.
If you get a cold or other infection while taking this medicine, call your doctor or health care professional. Do not treat yourself. The medicine may decrease your body's ability to fight infections.
The medicine can cause unusual growth of gum tissue and can make your gums bleed. Practice good oral hygiene, and be careful when brushing and flossing your teeth. See your dentist regularly.
Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information.
This medicine may increase your risk for certain types of skin cancer, especially if you have psoriasis. To decrease your risk, were protective clothing, including hats, and use sunscreen with a high protection factor when exposed to the sun. Avoid using tanning beds.
Some products may contain alcohol. Ask your pharmacist or healthcare provider if this medicine contains alcohol. Be sure to tell all healthcare providers you are taking this medicine. Certain medicines, like metronidazole and disulfiram, can cause an unpleasant reaction when with taken alcohol. The reaction includes flushing, headache, nausea, vomiting, sweating, and increased thirst. The reaction can last from 30 minutes to several hours.